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If you run a laboratory and want to make sure that your operations are efficient and the results often accurate, you’d want to invest in the best kinds of equipment. And one such device would be the hematology analyzer machine. This is a crucial piece of equipment, especially with the COVID-19 pandemic when tests need to be done fast and results are obtained quickly.

And though PCR tests have been the key type of testing needed to determine if an individual has COVID-19 or not, it would appear that there is hope and the possibility of identifying COVID-19 patients by running blood tests through the hematology analyzer. But what exactly is this equipment, and how does it work?

What is a hematology analyzer used for?

Also known as hematology automation, the hematology analyzer can be defined as the device used to run blood tests, specifically, complete blood counts (CBC) or the hemogram. This equipment is designed to perform both the qualitative and quantitative analysis for the formed elements of the blood, specifically the red blood cells or erythrocytes, white blood cells or leukocytes, and platelets (also known as the thrombocytes). In most cases, the hematology analyzer is used to assess patients’ general health status while also detecting the potential for all underlying diseases. In other words, the hematology analyzers offer immediate essential information that would affect the patient’s diagnosis and treatment.

The hematology analyzer is ideally used in medical analysis laboratories and even in hospitals that have hematology units. There also are some analyzers used in veterinary units.

So, how is the hematology analyzer used to identify the individuals suffering from COVID-19?

Since the outbreak of the SARS-CoV-2 virus in Wuhan, China, towards the end of 2019, the subsequent high mortality rates from the severe cases of the acute respiratory syndrome, as well as the long term consequences of the disease that include an impairment of the patients’ tolerance to glucose, lipid metabolism, and pulmonary fibrosis, along with the many changes to the blood, the PCR testing techniques are no longer as efficient, hence the need for alternative testing methods.

Machine learning appears to be the most promising solution to beat or enhance the performance of PCR testing and the prediction of COVID-19 in the standard laboratory and hematological tests. To detect the hematological and immunological changes that are associated with COVID-19, test techniques like flow cytometry are employed. In modern laboratories, hematology analyzers are employed, and flow cytometry is the most common method used to test for SARS-CoV-2.

How do I choose a hematology analyzer Machine for my Lab?

choose a hematology analyzer

If you are looking for a hematology analyzer for your lab, here are some of the important considerations you need to think about:

Applied Technologies – Type of Hematology Analyzer or the Analyzer’s counting method

To ensure the best results, different types of hematology analyzers are used in the lab. These promise accurate and highly reliable/ efficient results. These main types of hematology analyzers are as follows:

  • Flow cytometry

Flow cytometry

This is the most expensive and the most sophisticated method for hematology analyzers, but it also offers reliable results. The flow cytometry works by moving the blood cells in the narrow glow before the laser beam. The laser beam then hits the cells one after the other, with the light detector capturing the light that is reflected from the cells. Thanks to the function of this machine, it is also referred to as laser flow cytometry.

There is also fluorescence flow cytometry that works just like laser flow cytometry. The only difference between the two is that they have different methods/ ways of blood cell detection. What exactly does this mean? In addition to counting the cells, the equipment will also analyze the cells’ shapes and the internal and external structure of the cells.

  • Electrical Impedance

This is the other technique used in hematology but is more ideal when determining the total number and volume of the thrombocytes and erythrocytes. In this case, the EDTA blood to be tested is diluted using an isotonic solution inside this equipment; then, it’s aspirated via the capillary opening. The sample cells are then moved one after the other in an electrical voltage field where an electric pulse is passed, and different results are obtained based on the size of the cells. The electrical resistance and pulse passed through the blood sample make it easy for the large and the smaller cells to be differentiated and counted.

  • Laser Scattering

Laser scattering is the other hematology analyzer that determines the total cell volume in a test sample and the size distribution of the particles. For the measurement, angular variations are also determined based on the intensity of light scattering when laser beams are passed through the scattered particles. The larger cell particles will scatter the light at smaller angles than the smaller particles that scatter light at a larger angle. With these angular differences, you can easily calculate the sizes of the particles.

Types of parameters that need to be tested

  • Red Blood Cell Counting

Generally, it is possible to count the red blood cells using the hematology analyzer, which is done using the optical and impedance methods. You will be happy to know that even the smaller hematology analyzers are capable of testing and providing specific details of the RBC, such as the HCT, MCV, MCH, and MCHC.

On the other hand, the bigger automated hematology analyzers will give specific and more detailed information on things like the morphology of the red blood cells and the RDW. The RDW histogram is important as it allows you insights into the distribution of the red blood cells.

The red blood cells are also counted alongside the platelets. In many cases, however, testing these two types of cells could result in abnormal counts for the red blood cells, especially in the presence of elements like cold agglutinins, cryoglobulins, and lipids.

The most common parameter measured abnormally would lead to more abnormalities, especially in the red blood cell indices, especially the mean cell hemoglobin content or MCHC. But using the most sophisticated hematology analyzers often ensures an easy and efficient capacity for flagging any potential causes of the spurious red blood cells, among other parameters. Note that the hematology analyzers lack the ability to produce scattergrams for white blood cells in sensitive situations.

  • Running White Cell Differentials

This is the other important factor that determines whether the analyzer is suitable for use in your setting or not.

Essentially, the analyzer’s effectiveness is its ability to differentiate the different types of white blood cells. This is important because most of the analyzers on the market don’t allow for the differentiation of white blood cells.

And depending on the level of complexity and the size of the analyzer, you will come across 3-part, 5-part, and 5-part differentials. These devices also use different techniques in determining the white cell differentials, all grouped broadly into impedance, optical, and flow cytometry methods. In most cases, the analyzer employs these three methods for data gathering/ collection.

The large analyzers offer 5-part differentials, and others offer 7-part differentials, all featuring large immature cells – the blasts and the immature granulocytes.

  • Hemoglobin Measurement

This measurement option is based on the traditional method, the hemoglobin-cyanide method, in which the sample is diluted using the cyanmethemoglobin reagent to convert hemoglobin into methemoglobin. The results then combine with the potassium cyanide, forming the stable cyabmethemoglobin, and the color intensity of the reaction read on the photodetector to get the exact hemoglobin concentration.

  • Reticulocyte Count

This is the other test done by the hematology analyzer. The blood sample’s reticulocytes are tested by staining the RNA strands in the red blood cells using the nucleic acid, supravital, and fluorescent dyes. In this test, the total amount or level of fluorescence is directly proportional to the RNA present in the tested cells. To determine the level of reticulocytes in the sample, fluorescent flow cytometry is the test method of choice given its sensitivity in deficient concentrations, even in the presence of giant platelets.

Other Factors:

  • Point of Care (POC)

The hematology analyzers that make use of the POC are the ones that only give results for HCT and HB. These analyzers offer great results for the testing cell differentials for monocytes, lymphocytes, and granulocytes, along with the platelet counts, HB, HCT, and MCHC.

  • Automated Morphological Reviews and Slide Makers

Hematology Automated Morphological

These analyzers are designed to automate the preparation and staining of the slides. These solutions are often sold as part of the hematology solutions, but they could also be sold as standalone parts.

Other considerations:

  • Robotics & Automation – The analyzer you select should be compatible with your existing track.
  • Storage – the storage system for the analyzer should connect to your existing archiving system.
  • Random Access – The analyzers should have reliable random access capabilities. The STAT samples should be placed on the analyzer with ease and without running them as a batch.
  • Maintenance and Downtime – Ensure that the downtime is accounted for and the analyzer can run well or be covered by another analyzer during downtimes.
  • Cap Piercing – The best analyzers are considered the high-throughput analyzers, and these are either the closed tube sampling or the cap piercing analyzers.
  • Quality Control Management – The best hematology analyzers should have a control data management system for the best results.
  • Types of reagents to be used
  • Whether the analyzer system is open or closed vial testing modes, the open vial testing systems offer a high precision level and allow for complete blood count tests in just a minute, even in the most complex test samples. The closed vial processing system, on the other hand, is easier to run and allows you to test larger volumes of the samples while preventing leakages and spillage. Note that the hematology analyzers allow for the automatic piercing of the vials.
  • 3 and 5-Part Counts

The neutrophils and the lymphocytes are the relevant white blood cell types tested by the analyzer—the 3-part analyzer tests for the monocytes. The 5-part analyzers, on the other hand, are more precise, and they also run complete/ full blood counts for WBC into lymphocytes, neutrophil cells, monocytes, basicytes, and neosinocyte. The latter cost is more than the 3-part analyzers.

  • 3D VCS Technology

This analyzer boasts 3D VCS technology which allows for RBC analysis. It boasts the highest level of specificity, sensitivity, and efficiency in blood cell analysis. It determines the internal structure of the cells (granularity, nuclear lobularity, and the features on the cell surface) and their sizes.

  • Automatic Flagging Capabilities

Since the hematology analyzers can identify abnormal cells, you wouldn’t have to determine or review the cells within the right measurements manually. The reliability of the flagging system will, however, depend on the model of the hematology analyzer. So, first, check the analyzer’s specificity, sensitivity, and efficiency before settling on a specific analyzer model. You could also opt for the programmable models that easily set the measurements and the range for the normal cells, making it easy for you to flag the cells that are not within the specified limits for the normal cells.

Other features to keep under consideration:

  • The need/ necessity for auto-samplers
  • Whether you require a specific system for the preparation and the staining of the slides
  • Whether there is a need for analysis of the CRP (C-Reactive Protein)
  • Review of the application demands

The analyzers handling about 60 samples per hour would be ideal for basic units capable of delivering reliable and accurate results. But for the intuitive and hands-free devices, the advanced and fully automated machines would be ideal, especially in in-vitro diagnostics. For example, to detect abnormal cells, you need something with an abnormal flagging system like the Sysmex SF-3000. The best analyzers are the 3-part options that count lymphocytes, neutrophils, and monocytes, although the 5-part analyzer works well when the complete WBC analysis is required.

Think of the following functions:

  • The authorization type prescribed
  • The primary use of the analyzer and its compatibility with other units
  • Types of diseases, conditions, and analytes to test for
  • Specimens or samples to use the analyzer with
  • Automation features and connectivity
  • Maximum throughput and capacity
  • Training time needed for the analyzer, and the technical support necessary
  • Accessories, capabilities, and features
  • Budget

Being long-term investments, think of the practicality of the analyzer, the applications available, and the well-calibrated analyzers from reliable brands. New and refurbished analyzers would be a great option for you,

  • Equipment capacity and Workspace available

The bulkier analyzers are ideally heavy-duty pieces suitable for completing and processing multiple parameters and hundreds of samples for different operations. However, you’ll need the smaller hematology analyzers if you have a small laboratory space.

  • Service life plus maintenance

You’d have to spend more on the hematology analyzer if you want guaranteed long-term function and reliability. To ensure this, seek the ISO-Certified hematology analyzers since these are high-quality and reliable equipment you could use.

Also, learn about the effort needed to maintain the analyzer in the long term. The best analyzers call for zero-to-no maintenance needed.

How Hematology Analyzer Machine Identifying COVID-19 Patients

Hematology Analyzer Machine Identifying COVID-19

Hematology analyzers are ideal for testing for the presence of SARS-CoV-2 viruses in blood samples. The most common test used is flow cytometry. In addition to machine learning and artificial intelligence, the hemocytometric parameters for the immunocompetent cells in the peripheral blood cells like neutrophils, lymphocytes, or monocytes were quite high in the COVID-19 patient, unlike the ones that aren’t infected. From the results, the COVID-Positive patients had much different neutrophil-side fluorescence, neutrophil-forward scatters high fluorescent lymphocytes, and reactive MONOs than the individuals who weren’t infected.

Comparison of the best Hematology Analyzer machine for a clinic laboratory or research testing.

1. ABX micros 60 ($1,585.00)

ABX Micros 60

What is Abx Micros 60?

The ABX Micros 60 is an automated hematology analyzer used in medical laboratories to conduct in-vitro diagnostics testing of full blood specimens, full blood component concentrates, and platelet PRP samples. The equipment has been configured to utilize impedance technology and photometry as its primary measurement methods. It also uses stepper motor technology, enabling it to carry out its functions without using a compressor. 

Overview of ABX Micros 60

The ABX Micros 60 comes equipped with a sample tube holder and which has been designed to utilize multiple tube sizes. The equipment also uses an optional LiteDM software that provides comprehensive patient and QC data management. And with the USB connection option, technicians can archive patient and QC results and even download the QC target values. 

ABX Micros 60 also features a unique PAC system equipped with an innovative ABX patent; it comes ready to use and will simplify your lab organization. The Lite DM connectivity feature allows experts to add up to four connections and complete a micros 60. The ABX Micros 60 that utilizes light DM can integrate with third-party devices, such as the urine strip readers, the Tosso AIA 360, and the Picollo express chemistry analyzer, among others. 

Performance of the ABX Micros 60 

The ABX Micros 60 simplifies work in the lab given the easy-to-use QC data screens that allow clients to upload and store several lots of quality control using the light dm software. Patient results are displayed in a clear format, and interpreting the results has been simplified through the highlighted values in blue and red. Blue indicates low results, and red indicates high results. Clients can also record their routine maintenance in the log for inspection and can review a patient’s cumulative history of results at a glance. The Incorporated light DMV software enables simple navigation and reporting; it encourages easy back-up and restores and archives patient’s results. 

The ABX Micros 60 is a zero-maintenance system and is widely recognized for its reliability and ability to provide high-quality results. The ABX microsampling utilizes 10 microliters of whole blood per analysis while the liquid valves ensure precise volume and reliability. 

2. Advia 2120i ($8,400.00)

Advia 2120i

What is Advia 2120?

Advia 2120 is a high-volume hematology analyzer and has been designed to streamline workflow. This lab equipment obliterates the manual steps usually implemented to maximize productivity and is conveniently equipped with an auto slide for efficient first-pass accuracy.

Overview of the Advia 2120i

Advia technology utilizes peroxidase staining, which is considered the Gold standard in differential testing. The methodology has been established to provide a secondary white cell count that works as an inner QC check that detects sample integrity. Advia 2120i enables direct measurement of the intracellular hemoglobin, providing sensitive and specific RBC morphology, which enables accurate and early detection of disease states. 

The unit also isolates and identifies disease states through the CSF and CHr testing capabilities. Advia 2120i is also famous for the unique cytochemical differentiation of the lymphoid and myeloid cells. With the inclusion of the six parameter differential, experts are sure of additional clinical information.  The unit is also known for enabling accurate platelet counts. Still, in the clinically significant range, it excludes the microcytic red cells and the cell fragments, thus minimizing the number of manual counts and redundant, expensive platelet transfusion. 

Performance of the Advia 2120i

Advia 2120i is designed to deliver Gold standards in testing methodology; the equipment will, therefore, automate hematology workflow; it will easily differentiate between the microcytic anemias utilizing the RBC and reticulocyte technology. The equipment is also known to maximize the effectiveness of costly platelet transfusions and offers correct results. Notable is that the above is achievable even when the platelet is at its lowest levels. 

The unique high-volume hematology solution enables enhanced productivity without compromising on quality. Maintenance has also been simplified with the unifluidics technology, which is achieved through reduced fluidics, automated daily cleaning, and the eliminated pinch valves. 

Advia 2120 allows lab technicians to expand their capabilities. The unit boasts of integrated and automated solutions from the Siemens Healthineers. Advia 2120i is best utilized by labs that need to upgrade to efficient and accurate systems to project an increase in their productivity needs. Most importantly is that the Advia 2120i enables scalable automation solutions. 

3. Sysmex XN 1000 ($7,750.00)

Sysmex XN 1000

What is Sysmex Xn 1000?

The Sysmex Xn 1000 is a hematology analyzer designed for use in the modern clinical laboratory. The Xn 1000 features a compact design and enables innovative flow cytometry. Lab technicians can use the equipment to achieve the most exhaustive CBC and differential obtainable thanks to the fluorescent technologies. 

Overview of the Sysmex Xn 1000 

The design of the Sysmex Xn 1000 makes it intuitive to operate. The unit features a touch screen and a graphical user interface that makes manipulation a breeze. It will occupy a small footprint in your lab thanks to its compact size and comes equipped with optional reagent container sizes. 

The hematology analyzer offers advanced services. Thus, the lab technicians can be provided with industry-leading customer service, which is accessible both on the phone and in the field. Other important services include reagent management systems, remote monitoring, quality assurance programs, and managed calibration programs. 

The unit also offers automatic flex measurements in case the results are unreliable. The turnaround times are short. The unit can also be integrated with a slide maker and stainer. 

Performance of the Sysmex Xn-1000

Sysmex Xn-1000 is a high-performance unit and will provide its users with reproducible results in the shortest time possible. Re-analyzing the same unreliable results achieve this samples the automated equipment effectively minimizes manual intervention without affecting the turnaround time. The unit has been proved to manage the reagents easily and integrates the reagents in the optional analyzer wagon. 

Sysmex Xn-1000 is scalable and can be integrated with the relevant diagnostic applications. And with regards to what has been installed, the units rerun and reflex configurations will perform a range of rule-based tests. And the resulting positive samples will automatically be fed to an extended measurement. Notable is that the extended measurement is only valuable if its performance will contribute to diagnostic value. 

The hematology analyzer integrates with optional software and can be networked with other xn solutions in different locations. It can process up to 100 samples in one hour and features advanced clinical parameters. 

The Xn 1000 features an upgradable design and can incorporate the new XN-20 CBC analyzer, which is a perfect alternative to the Xn-10 that comes standard with the Xn-1000. The purpose of the Xn-20 is to offer an extra analysis channel.  

4. Sysmex XP 300 ($3,295.00)

sysmex xp 300

What is Sysmex XP 300? 

Sysmex XP 300 is a hematology analyzer specially developed for use in a clinic satellite laboratory. The unit is not only robust but highly reliable and comes equipped with the most advanced diagnostics. Basically, it is an automated 3-part differential hematology analyzer known to provide high-quality diagnostic results. 

Overview of the Sysmex XP 300

Sysmex Xp 300 is built with innovative technology, enabling it to perform rapid and accurate analysis of a 17-parameter CBC, which includes automatic floating discriminators, histograms for RBC, WBC, and PLT. The hematology analyzer is also known to produce accurate results, the unit is elementary to operate and maintain, and training is required to exploit its full potential. 

The Sysmex XP 300 is also safe and secure to use. This offers two reagents, diluent and lyse, to achieve complete results. It features a non-toxic, biodegradable reagent system. It is compact thus will occupy a small footprint in the clinic satellite laboratory. The XP 300 is the perfect backup for Sysmex X-series and the Xn-series analyzers. 

The unit has a reliable network capability, thus enables data transfer to LIS through a LAN or a serial port. And also features a bi-directional interface that has been made complete with an intuitive touch screen menu. 

Performance of the Sysmex XP 300

Sysmex XP 300 has been established to provide a CBC with up to 8 reportable parameters. The hematology analyzer also providers a 3-part WBC differential that comes complete with an Absolute Neutrophil count. Important to note is that the results will include histograms for the WBC, RBC, and the PLT. Sysmex XP 300 offers a high accuracy level, which is achieved by utilizing the automatic floating discriminators. 

The Sysmex XP 300 features an effective Sysmex technology, has incorporated a simple start-up menu, and sampling is achieved by selecting a single-button menu. The unit additionally offers reliable results and utilizes the direct current detection method. 

5. Sysmex XN 550 ($37,777.00)

Sysmex XN 550

What is Sysmex Xn 550? 

The Sysmex Xn 550 is a state-of-the-art 5-part differential hematology analyzer whose configuration enables users to run single samples safely and in closed mode. The unit is characteristic of an integrated information processing unit, and operating the unit has been simplified by incorporating the LCD color touchscreen. 

Overview of the Sysmex Xn-550

The Xn-550 is made with an automated sampler and improves workflow productivity through its continuous loading feature and the rerun and reflex functionality. The unit also features effective Sysmex technologies for determining hemoglobin, and the design of the sampler allows for both open and closed tube analysis.

The unit features a multi-colored touchscreen display and which has been embedded with an intuitive graphical user interface that helps support a user’s routine tasks. Lab technicians will also be furnished with a reagent management system designed to calculate the remaining tests and expiry dates, thus enabling efficient reagent usage tracking. 

Sysmex Xn-550 is highly flexible and only requires up to 25l of aspiration volume to conduct the whole blood and the low WBC mode. The unit is additionally equipped with an Auto diluent dispensing function usually used for the dilution of samples. 

Performance of the Sysmex Xn-550

Sysmex Xn-550 falls under the Xn-L category and is known to deliver specialist solutions for facilities that specialize in niche diagnostics. Thus some of the incorporated dedicated functionalities can come in handy when used in a dialysis center to monitor patients. The unit also suffices for use in neurology wards, offering dedicated analysis for different body fluids. And in Oncology, the Xn-l will offer precise and accurate measurements of the leukocytopenia samples.

The Sysmex Xn-550 is a future-proof hematology analyzer and can be upgraded by simply adding new clinical and productivity values. The unit is flexible and can thus connect to Sysmex Extended IPU as the laboratory demands become more dynamic. 

6. Sysmex XS-1000i ($3,400.00)

Sysmex XS-1000i

What is the Sysmex Xs-1000i?

The Sysmex Xs-1000i is an automated hematology analyzer and which has been configured to generate full blood counts but with a five-part leucocyte differential. The Xs-1000i streamlines the technician’s workflow and will test and produce results for 60 samples every hour. 

Overview of the Sysmex Xs-1000i

The XS-1000i is highly beneficial for small labs and has streamlined workflow by enabling analytical processes with closed tube auto sampling. The unit is also versatile and can thus be used with the Sysmex WAM, a decision support software for the clinical laboratory. The hematology analyzer is equipped with an intuitive software menu and an onboard help key necessary for rapid troubleshooting. 

The high-performance analyzer enables remote monitoring for maximum uptime and offers closed mode aspiration for single tubes. The Xs series is additionally unique in its functionality as realized in the aspiration volume of only 20l, and this feature can be quite beneficial for the pediatric and neonatal samples. 

The user maintenance for the Xs-1000i has also been reduced, thus experiences minimal automatic shutdown time. 

Performance of the Sysmex Xs-1000i

Sysmex Xs-1000i can offer even greater performance when integrated with other relevant software such as the SNCS. The latter is a Sysmex network communication system that enables fast and secure communication from the analyzer to the Sysmex severs but utilizes an outbound internet connection. 

The unit is also equipped with a novel sample explorer that simplifies sample management. The hematology analyzer also offers a complete differential blood count, and that is for all the white blood cell population. Users will also be furnished with an excellent determination of the red blood cells and platelets, which comes complete with hydrodynamic focusing. 

Most importantly, technicians will also be impressed with the hemoglobin measurements because the XS-series has been configured to retain a dedicated hemoglobin channel. 

The Sysmex Xs-1000i is best utilized by small laboratories that are performance-oriented and must deliver accurate results. The hemoglobin analyzer will simplify workflow in the laboratory and offer high performance when integrated with the relevant software.

7. Mindray BC 2800 ($2,100.00)

Mindray BC-2800

What is the Mindray BC 2800? 

The Mindray BC 2800 is an automatic hematology analyzer that features 19 parameters for CBC testing and microsampling technology. It is equipped with simple and easy-to-use software and offers accurate results. Notable is that for the unit to retain effectiveness, users must ensure that it is routinely cleaned.

Overview of the Mindray BC 2800

The Mindray BC 2800 is perfect for small laboratories and comes equipped with a large color display, thus will furnish the user with 19 parameters and 3 histograms on one screen. It is equipped with a huge database, so it has also been configured to offer a comprehensive patient data search function. The analyzer also boasts of a huge storage capacity and will effectively store up to10 000 patient results with histograms. 

Most importantly, data input doesn’t have to be manual; thus, lab technicians can also input data using a barcode scanner, a keyboard, or a keypad. The unit further offers comprehensive QC programs, and which include the L-J and X-B analyses. 

What’s more, the Zap aperture and the flush function conveniently avoids clogging, and the hemoglobin analyzer also features automatic internal and external probe cleaning. One major downside of this unit is that it is maintenance intensive and will require background testing. 

Performance of the Mindray Bc 2800

When it comes to the performance of the Mindray BC 2800, it has been established to be highly accurate and reliable. And with a throughput of up to 30 tests per hour, thus can effectively suffice the needs of a small library. Mindray BC 2800 is compact thus occupies a small footprint in your laboratory. The unit also boasts a built-in thermal decoder recorder, which is made complete with an optional external printer. The above enables a streamlined workflow. 

The Mindray BC 2800 is a high-performance hematology analyzer for small laboratories. The unit is equipped with advanced technology; it is highly durable and enables a streamlined workflow. It also comes equipped with an intuitive interface; users must however note that it is a maintenance-intensive unit. 

8. Mindray BC 3000 plus ($2,250.00)

mindray BC-3000 Plus

What is Mindray BC 3000 Plus 

The BC 3000 plus is a hematology analyzer best utilized by the mainstream laboratory; it is a 19 parameter benchtop automatic analyzer with a throughput of up to 60 samples per hour. Some of its best functions are lyzing, diluting, mixing, rinsing, and unclogging. 

Mindray BC 3000 Plus overview  

The Mindray BC 3000 plus hematology analyzer is an all-around safe unit that utilizes the original cyanide-free reagents known to ensure a safe and biohazard-free operation. The equipment has incorporated a user-friendly interface that enables a smooth workflow, and with the touch of a button, users will be able to retrieve the results. 

The unit offers a low sampling volume of up to 13l whole blood per test, and it is less maintenance intensive because of the incorporation of the auto cleaning system. Mindray BC 3000 plus is highly reliable and accurate, and this has been proved by its ability to offer a fully automatic calibration and its unique fresh blood calibration program. 

The unit also boasts a powerful customized software design that offers different patient data review modes; the unit is also equipped with programmable print formats. 

Performance of the Mindray BC 3000 Plus 

The high-performance Mindray BC 3000 Plus is equipped with two counting modes: the whole blood and the pre-diluted. Most of its functions are automatic. Thus the technician can focus on other important matters. For a small lab Mindray, BC 3000 plus is a high capacity unit, and its storage capacity can accommodate up to 35,000 sample results complete with histograms. 

The Mindray BC 3000 plus is a quantitative and automated analyzer and leucocyte differential counter used in Vitro Diagnostics. Therefore, this unit is the perfect analyzer to be utilized by the mainstream labs that are focused on quality results. 

9. Sysmex XN-2000 ($8,000.00)

Sysmex XN-2000

What is the Sysmex Xn-2000?

The Sysmex Xn-2000 is a hematology analyzer that utilizes impedance, cytometry, and optical cytometry to determine the tested hematological parameters. The Xn-2000 features better technology when compared to its predecessors; it is equipped with an integrated co-primary hematology system made with two analytical modules. And is, therefore, capable of processing up to 200 samples within one hour. 

Overview of the Sysmex Xn-2000

The Xn-2000 has been designed with two analysis modules and equipped with all the necessary diagnostic applications. The rerun and reflex features of the hematology analyzer enable the unit to carry out both basic and extended testing. Notable is that both modules have been designed to process rack samples simultaneously. 

More importantly, is that they can cater to any sample without compromising on speed. Operating the unit is not labor-intensive. Thus, technicians will not have to select and reload samples manually. What’s more, the utilization of two modules offers enhanced security when carrying out the lab’s routine because the unit does have an integrated backup. 

The Sysmex Xn-2000 is also versatile and flexible in that it can be networked with other Xn’s to come up with multiple location installations. 

Performance of the Sysmex Xn-2000

The Xn-2000 hematology analyzer happens to be the first co-analyzer to be put out in the market; the unit is characteristic of two instruments in one platform. The two instruments are identical and have been equipped with the same parameters and configured to balance the load automatically. The unit also boasts of a backup instrument, which is the same as the primary. Among the analyzer’s most important benefits are the co-primary backup process and its minimal instrument maintenance.

Sysmex Xn-2000 is the perfect pair for carrying out both basic and extended testing. The unit does offer a flexible throughput but is highly dependent on the workload. It also offers short turnaround times and boasts of a unique integrated backup concept.

10. Beckman Coulter DXH 800 ($15,999.00)

Beckman Coulter DxH-800

What is the Beckman Coulter Dxh 800? 

The Beckman Coulter Dxh 800 is a fast and reliable hematology analyzer incorporating innovative upgrades and offering comprehensive testing in a single operation. The analyzer configuration ensures that it overcomes sample challenges and minimizes workload by eliminating some of the steps. 

Overview of the Beckman Coulter Dxh 800

The Dxh 800 has enhanced the first-pass accuracy with its advanced algorithms and automated intelligent morphology. The unit also overcomes cellular independence using the multi-angle laser scatter and the coulter principle impedance. 

The hematology analyzer’s configuration increases laboratory efficiency, thus enables connectivity to up to three Dxh800 analyzers. The unit also offers enhanced testing capabilities, thus conducting high-priority tests quickly using the true STAT interrupt. 

Performance of the Dxh 800

The Dxh 800 is a fully automated hematology analyzer featuring the new technology to perform whole blood and body fluids tests. The analytical module of the Dxh 800 is equipped with a state-of-the-art specimen transport module that utilizes magnetic force to move cassettes to different locations with no exposed parts. 

The above feature further ensures operator safety. The unit additionally features built-in connectivity that enables integrated automation. The above then means users won’t need a track, consequently enabling a work cell by connecting a different Dxh 800. The in-built connectivity feature also enables the integration of a slide maker strainer for enhanced functionality. 

The Dxh is also highly flexible thanks to its onboard extended decision rules capability; laboratories will, therefore, be able to create decision rules up to the patient level. The unit also offers automated repeat reflex testing, and by utilizing a simple decision, the rule will take the cassettes back to the analytical module to reanalyze the specimen. This feature makes it easy when it comes to searching for samples for reanalysis. 

The DXh 800 improves quality and productivity and effectively reduces cost with the incorporated automation and information solutions. The unit enables timely patient care without the need to procure additional samples with auto-release reflex testing. 


Thanks to advanced technologies, COVID-19 tests are done by running blood tests to determine the volumes and the levels of immune cells in the blood of the infected individuals. All you would need is the best hematology analyzer machine to get your laboratory setup.

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